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常見內源代謝物液相色譜-四極桿-飛行時間質譜圖集 讀者對象:可供醫(yī)學、生命科學、環(huán)境科學等領域從事代謝組學研究的研究人員、分析人員作為工具書使用。
本書總結了346種常見的內源代謝物,包含糖類、脂類、氨基酸、核苷等初級代謝物,以及黃酮類、多酚類和含氮化合物等次生代謝物,在UPLC-QTOF固定的色譜和質譜條件下,分別使用正源和負源模式采集的色譜圖(含保留時間)、一級高分辨質譜圖、同位素豐度圖和常用碰撞能(35±15)V條件下的二級高分辨全掃質譜圖。
本書展示的圖譜可大大提高內源代謝物的定性準確度,減少假陽性或假陰性的現象,確保相關領域的研究穩(wěn)步進行,可供醫(yī)學、生命科學、環(huán)境科學等領域從事代謝組學研究的研究人員、分析人員作為工具書使用。
張艷偉,農業(yè)農村部環(huán)境保護科研監(jiān)測所,副研究員,南開大學環(huán)境科學專業(yè)博士,研究方向為環(huán)境污染物農業(yè)環(huán)境行為與生態(tài)毒理機制,供職于農業(yè)農村部環(huán)境保護科研監(jiān)測所,主要利用代謝組學工具在探究環(huán)境污染物對生物體的生態(tài)毒性及其機制方面做了大量工作。主持國家自然科學基金1項,天津市自然科學基金1項,國家重點研發(fā)項目子課題1項,農業(yè)部財政專項3項,中央科研院所基礎科研業(yè)務費項目2項,教育部重點實驗室開放基金1項。申請專利4項,授權2項,發(fā)表SCI論文10余篇。
4-Acetamidobutanoic Acid 4-乙酰氨基丁酸/1
Acetylcholine 乙酰膽堿/2 Adenine 腺嘌呤/3 Adenosine 腺苷/4 Adenosine 2′,3′-Cyclic Monophosphate 2′,3′-環(huán)磷酸腺苷/5 Adenosine 3′,5′-Diphosphate 3′,5′-二磷酸腺苷/6 Adenosine 5′-5′-Diphosphate 二磷酸腺苷/7 Adenosine 5′-5′-Diphosphoglucose 二磷酸葡萄糖腺苷/8 Adenosine 5′-Diphosphoribose 腺苷5′-二磷酸核糖/9 Adenosine 5′-Triphos-phate 5′-三磷酸腺苷/10 Adipic Acid 己二酸/11 Allantoin 尿囊素/12 Allose 阿洛糖/13 α-Aminoadipic Acid 2-氨基己二酸/14 4-Aminobutyric Acid 4-氨基丁酸/15 1-Aminocyclopropane-1-Carboxylic Acid 1-氨基環(huán)丙烷羧酸/16 2-Aminoethyl Dihydrogen Phosphate 乙醇胺磷酸酯/17 (2-Aminoethyl)Phosphonic Acid 2-氨基乙基膦酸/18 3-Amino-4-Hydroxy-benzoic Acid 3-氨基-4-羥基苯甲酸/19 3-Amino-5-Hydroxyben-zoic Acid 3-氨基-5-羥基苯甲酸/20 2-Aminoisobutyric Acid 2-甲基丙氨酸/21 2-Aminophenol 2-氨基苯酚/22 Aniline-2-Sulfonic Acid 2-氨基苯磺酸/23 Arachidic Acid 二十酸/24 Azelaic Acid 壬二酸/25 Benzoic Acid 苯甲酸/26 Betaine 甜菜堿/27 Biliverdin 膽綠素/28 Biotin 生物素(維生素H)/29 Bis(2-Ethylhexyl)Phthalate 鄰苯二甲酸二(2-乙基己)酯/30 Cadaverine 尸胺/31 Caffeic Acid 咖啡酸/32 Carnosine 肌肽/33 Catechol 兒茶酚/34 Cholic Acid 膽酸/35 Choline 膽堿/36 Cis-4-Hydroxy-D-Proline 順式-4-羥基-D-脯氨酸/37 Citraconic Acid 檸康酸/38 Citramalic Acid 檸蘋酸/39 Citric Acid 檸檬酸/40 Citrulline L-瓜氨酸/41 5′-CMP 5′-胞苷酸/42 Coenzyme A 輔酶A/43 Cortisol 皮質醇/44 Cortisol 21-Acetate 醋酸皮質醇/45 4-Coumaric Acid 4-羥基肉桂酸/46 Creatine 肌酸/47 3′,5′-Cyclic Amp 腺苷環(huán)磷酸酯/48 Cytidine 胞苷/49 Cytidine 2′,3′-Cyclic Monophosphate 胞苷2′,3′-環(huán)一磷酸/50 Cytidine 5′-Diphosphate 胞苷-5′-二磷酸/51 Cytidine 5′-Diphospho-choline 胞磷膽堿/52 Cytidine 5′-Triphosphate 5′-三磷酸胞苷/53 Cytosine 胞嘧啶/54 dAMP 2′-脫氧腺苷-5′-單磷酸/55 3-Dehydroshikimate Acid 3-脫氫莽草酸/56 2′-Deoxyadenosine 2′-脫氧腺苷/57 Deoxycarnitine ?麎A/58 Deoxycholic Acid 去氧膽酸/59 Deoxycorticosterone Acetate 醋酸去氧皮質酮/60 Deoxycytidine 2′-脫氧胞嘧啶核苷/61 2′-Deoxycytidine 5′-Monophosphate 2′-脫氧胞苷-5′-單磷酸/62 2′-Deoxycytidine 5′-Diphosphate 2′-脫氧胞苷-5′-二磷酸/63 2′-Deoxyguanosine 2′-脫氧鳥苷水合物/64 2′-Deoxyguanosine 5′-Diphosphate 2′-脫氧鳥苷-5′-二磷酸/65 2′-Deoxyguanosine 5′-Monophosphate 2′-脫氧鳥苷-5′-單磷酸/66 2′-Deoxyguanosine 5′-Triphosphate 2′-脫氧鳥苷-5′-三磷酸/67 Deoxyuridine 2-脫氧尿苷/68 2′-Deoxyuridine 5′-Monophosphate 2′-脫氧尿苷-5′-單磷酸/69 2′-Deoxyuridine 5′-Triphosphate 2′-脫氧尿苷-5′-三磷酸/70 Desmosterol 鏈甾醇/71 Dethiobiotin 脫硫生物素/72 D-Fructose 6-Phosphate 磷酸果糖/73 α-D-Galactose 1-Phos-phate 半乳糖-1-磷酸/74 D-(+)-Galacturonic Acid 半乳糖醛酸/75 D-(+)-Glucosamine D-氨基葡萄糖/76 D-Glucosamine 6-Phosphate D-氨基葡萄糖6-磷酸/77 D-Glucose 6-Phosphate D-葡萄糖-6-磷酸/78 D-Glucuronic Acid D-葡萄糖醛酸/79 D-Glucuronolactone D-葡糖醛酸內酯/80 2,6-Diaminopimelic Acid 2,6-二氨基庚二酸/81 1,2-Didecanoyl-Sn-Glycero-3-Phosphoch oline L-二癸酰基磷脂酰膽堿/82 Dihydrofolic Acid 二氫葉酸/83 5,6-Dihydrouracil 二氫尿嘧啶/84 2′,4′-Dihydroxyace-tophenone 2′,4′-二羥基苯乙酮/85 2,3-Dihydroxybenzoic Acid 2,3-二羥基苯甲酸/86 2,5-Dihydroxybenzoic Acid 2,5-二羥基苯甲酸/87 3,4-Dihydroxybenzoic Acid 原兒茶酸/88 3,4-Dihydroxy-L-Pheny-lalanine 3,4-二羥基-L-苯基丙氨酸/89 Dihydroxymandelic Acid 3,4-二羥基扁桃酸/90 3,4-Dihydroxyphenyl Glycol 3,4-二羥基苯基二醇/91 2,4-Dihydroxypteridine 2,4-二羥基蝶啶/92 2,6-Dihydroxypyridine 2,6-二羥基吡啶/93 2,4-Dihydroxypyrimidine-5-Carboxylic Acid 2,4-二羥基嘧啶-5-羧酸/94 3,5-Diiodo-L-Thyronine 3,5-二碘-L-甲狀腺素/95 3,5-Diiodo-L-Tyrosine 3,5-二碘-L-酪氨酸/96 Dimethylbenzimidazole 二甲基苯并咪唑/97 D-Lactose D-乳糖/98 DL-5-Hydroxylysine 5-羥基-DL-賴氨酸/99 DL-Normetanephrine DL-去甲腎上腺素/100 D-Mannosamine D-甘露糖胺/101 D-Mannose 6-Phosphate D-甘露糖-6-磷酸/102 Docosahexaenoic Acid 二十二碳六烯酸/103 Dopamine 多巴胺/104 D-Ornithine D-鳥氨酸/105 D-Pantothenic Acid D-泛酸/106 D-(-)-3-Phosphoglyc-eric Acid 3-磷甘油酸/107 D-(+)-Raffinose 棉子糖/108 D-Ribose 5-Phosphate D-核糖-5-磷酸/109 D-Saccharic Acid D-糖酸/110 D-Tryptophan D-色氨酸/111 Elaidic Acid 反油酸/112 Epinephrine 腎上腺素/113 Erucic Acid 芥酸/114 Ethanolamine Phosphate 乙醇胺磷酸酯/115 Ethylmalonic Acid 乙基丙二酸/116 Flavin Adenine Dinucl-eotide 黃素腺嘌呤二核苷酸/117 Folic Acid 葉酸/118 Formyl-L-Methionyl Peptide N-甲;-L-蛋氨酸/119 Galactitol 半乳糖醇/120 Geranyl Pyrophosphate 香葉基焦磷酸/121 Glutaric Acid 戊二酸/122 Glycocholic Acid 甘氨膽酸/123 4-Guanidinobutyric Acid 4-胍基丁酸/124 Guanine 鳥嘌呤/125 Guanosine 鳥嘌呤核苷/126 Guanosine 3′,5′-Cyclic Monophosphate 鳥苷-3′,5′-環(huán)一磷酸/127 Guanosine 5′-Monopho-sphate 鳥苷酸/128 Heptadecanoic Acid 十七烷酸/129 Hippuric Acid 馬尿酸/130 Histamine 組胺/131 Homocystine 高胱氨酸/132 Homoserine 高絲氨酸/133 Homovanillic Acid 高香草酸/134 3-Hydroxyanthra-nilic Acid 3-羥基-2-氨基苯甲酸/135 4-Hydroxybenzaldehyde 對羥基苯甲醛/136 3-Hydroxybenzoic Acid 間羥基苯甲酸/137 4-Hydroxybenzoic Acid 對羥基苯甲酸/138 3-Hydroxybenzyl Alcohol 3-羥基苯甲醇/139 2-Hydroxybutyric Acid 2-羥基丁酸/140 3α-Hydroxy-5β-Cholanic Acid 石膽酸/141 10-Hydroxydecanoic Acid 10-羥基癸酸/142 12-Hydroxydodecanoic Acid 端羥基十二酸/143 5-Hydroxyindoleacetate 5-羥基吲哚-3-乙酸/144 4-Hydroxy-L-Phenyl-glycine L-(+)-對羥基苯甘氨酸/145 4-Hydroxy-L-Proline L-羥基脯氨酸/146 5-Hydroxy-L-Tryptophan 5-羥基色氨酸/147 4-Hydroxy-3-Methox-yphenylglycol 4-羥基-3-甲氧-基苯乙二醇/148 1-Hydroxy-2-Naphthoic Acid 1-羥基-2-萘甲酸/149 6-Hydroxynicotinic Acid 6-羥基煙酸/150 4-Hydroxyphenylacetate 4-乙酰氧基苯酚/151 3-(4-Hydroxyphenyl)Lactic Acid 3-(4-羥基苯基)乳酸/152 3-(2-Hydroxyphenyl)Propionic Acid 3-(2-羥基苯基)丙酸/153 4-Hydroxy-2-Quinolin-ecarboxylic Acid 氯氨酮/154 Hypoxanthine 次黃嘌呤/155 4-Imidazoleacetic Acid 4-咪唑乙酸/156 Indole-3-Acetaldehyde 吲哚-3-乙醛/157 Indole-3-Acetamide 3-吲哚乙酰胺/158 Indole-3-Acetic Acid 吲哚乙酸/159 Indole-3-Ethanol 色醇/160 Indoxyl Sulfate 硫酸吲哚/161 Inosine 肌苷/162 Inosine 5′-Diphosphate 肌苷-5′-二磷酸/163 Inosine 5′-Triphosphate 肌苷-5′-三磷酸/164 5′-Inosinic Acid 5′-肌苷酸/165 Isopentenyl Pyroph-osphate 異戊烯焦磷酸/166 Itaconic Acid 衣康酸/167 Kynurenine 犬尿氨酸/168 L-Allothreonine L-別蘇氨酸/169 L-Anserine L-鵝肌肽/170 L-Arginine L-精氨酸/171 L-Asparagine L-天冬酰胺/172 L-Aspartic Acid L-天冬氨酸/173 Lauric Acid 月桂酸/174 Lauroylcarnitine 月桂酰肉桂堿/175 L-Carnitine 左旋肉堿/176 L-Cystathionine L-胱硫醚/177 L-Cysteine L-半胱氨酸/178 L-Cystine L-胱氨酸/179 Leucine 亮氨酸/180 Leukotriene B4 白三烯B4/181 L-Glutamic Acid L-谷氨酸/182 L-Glutamine L-谷氨酰胺/183 L-Histidine L-組氨酸/184 L-Histidinol L-組氨醇/185 Linoleate 亞油酸酯/186 γ-Linolenic Acid γ-亞麻酸/187 Lipoamide 硫辛酰胺/188 L-Isoleucine L-異亮氨酸/189 L-Lysine L-賴氨酸/190 L-Methionine L-蛋氨酸/191 L-Norvaline L-正纈氨酸/192 L-Phenylalanine L-苯丙氨酸/193 L-Pipecolic Acid L-2-哌啶酸/194 L-Proline L-脯氨酸/195 L-Rhamnose L-鼠李糖/196 L-Serine L-絲氨酸/197 L-Threonine L-蘇氨酸/198 L-Tryptophanamide L-色氨酰胺/199 L-Tyrosine L-酪氨酸/200 Lumichrome 光色素/201 L-Valine L-纈氨酸/202 Maleic Acid 馬來酸/203 Malonic Acid 丙二酸/204 Mandelic Acid 扁桃酸/205 Melatonin 褪黑素/206 Menaquinone 維生素K2/207 Meso-Tartaric Acid 內消旋酒石酸/208 3-Methoxy-L-Tyrosine 3-甲氧基-L-酪氨酸/209 3-Methoxytyramine 3-甲氧酪氨/210 1-Methyladenosine 1-甲基腺苷酸/211 3-Methylcrotonyl-CoA 3-甲基巴豆酰輔酶A/212 5-Methylcytosine 5-甲基胞嘧啶/213 3-Methylglutaric Acid 3-甲基戊二酸/214 Methylguanidine 甲胍/215 3-Methylhistamine 3-甲基組胺/216 Methyl Indole-3-Acetate 吲哚-3-醋酸甲酯/217 Methyl Jasmonate 茉莉酸甲酯/218 Methylmalonic Acid 甲基丙二酸/219 1-Methylnicotinamide 1-甲基煙酰胺/220 3-Methyl-2-Oxindole 3-甲基羥基吲哚/221 5′-Methylthioadenosine 5′-脫氧-5′-甲硫腺苷/222 6-Methylthiopurine 6-甲巰基嘌呤/223 Monomyristin 豆蔻酸甘油酯/224 Mucic Acid 黏酸/225 Myristic Acid 肉豆蔻酸/226 N-Acetyl-DL-Glutamic Acid N-乙酰-DL-谷氨酸/227 N-Acetyl-DL-Methionine N-乙酰-DL-蛋氨酸/228 N-Acetyl-DL-Serine N-乙酰-DL-絲氨酸/229 N-Acetylglycine N-乙酰-甘氨酸/230 N-Acetyl-L-Alanine N-乙酰-L-丙氨酸/231 N-α-Acetyl-L-Aspa-ragine N-乙酰-L-天門冬酰胺/232 N-Acetyl-L-Aspartic Acid N-乙酰-L-天門冬氨酸/233 N-Acetyl-L-Leucine N-乙酰-L-亮氨酸/234 N-α-Acetyl-L-Lysine N-乙酰-L-賴氨酸/235 N-Acetyl-L-Phenylal-anine N-乙酰-L-苯丙氨酸/236 N-Acetylneuraminic Acid N-乙酰神經氨酸(唾液酸)/237 N-Acetylputrescine N-(4-氨基丁基)-乙酰胺/238 N-Acetylserotonin N-乙;-5-羥色胺/239 N1-Acetylspermine N1-乙酰基精胺/240 N-Amidino-L-Aspartic Acid 2-胍基琥珀酸/241 Nervonic Acid 神經酸/242 N-Formylglycine N-甲酰甘氨酸/243 Nicotinamide 煙酰胺/244 β-Nicotinamide Adenine Dinucleotide(NAD) 煙酰胺腺嘌呤雙核苷酸/245 β-Nicotinamide Adenine Dinucleotide Phosphate Sodium Salt Hydrate 煙酰胺腺嘌呤雙核苷酸磷酸鈉鹽結合水/246 Nicotinamide Hypoxan-thine Dinucleotide Sodium Salt 煙酰胺核苷酸次黃嘌呤鈉鹽/247 Nicotinamide Mononu-cleotide β-煙酰胺單核苷酸/248 Nicotinic Acid 煙酸/249 Nicotinic Acid Adenine Dinucleotide Phosphate 煙酸腺嘌呤二核苷酸磷酸/250 N6-(δ2-Isopentenyl)-Adenine N6-異戊烯基腺嘌呤/251 3-Nitro-L-Tyrosine 3-硝基-L-酪氨酸/252 N-Methyl-D-Aspartic Acid N-甲基-D-天冬氨酸/253 N-Methyl-L-Glutamic Acid N-甲基-L-谷氨酸/254 N(π)-Methyl-L-Histidine 1-甲基-L-組氨酸/255 N-Ω-Methyltryptamine N(Ω)-甲基色胺/256 Nε,Nε,Nε-Trime-thyllysine 三甲基賴氨酸/257 Norleucine L-正亮氨酸/258 Octopamine 奧克巴胺/259 Oleic Acid 油酸/260 1-Oleoyl-Rac-Glycerol 單油酸甘油酯/261 O-Phospho-DL-Serine DL-O-磷酸絲氨酸/262 O-Phospho-L-Serine L-O-磷酸絲氨酸/263 Ophthalmic Acid 視晶酸/264 Orotic Acid 乳清酸/265 O-Succinyl-L-Homo-serine O-丁二酰-L-高絲氨酸/266 5-Oxo-D-Proline D-焦谷氨酸/267 Palmitic Acid 棕櫚酸/268 Palmitoleic Acid 棕櫚油酸/269 Paraxanthine 1,7-二甲基黃嘌呤/270 Petroselinic Acid 十八碳六烯酸/271 Phenylethanolamine N-苯基乙醇胺/272 Phenylpyruvic Acid 苯丙酮酸/273 Phosphocholine 磷酸膽堿/274 Phosphocreatine 磷酸肌酸/275 Phospho(enol)pyruvic Acid 磷烯醇丙酮酸/276 Phosphonoacetic Acid 乙酰磷酸/277 Protoporphyrin 原卟啉/278 Pterin 2-氨基-4-羥基蝶啶/279 Purine 嘌呤/280 Pyridoxal 5′-Phosphate 磷酸吡哆醛/281 Pyridoxamine 吡哆胺/282 4-Pyridoxic Acid 4-吡哆酸/283 Pyridoxine 吡哆醇/284 Pyrrole-2-Carboxylate 吡咯-2-羧酸/285 Quinic Acid 右旋奎寧酸/286 Quinoline 喹啉/287 Quinolinic Acid 喹啉酸/288 Reichstein′s Substance S脫氧可的松/289 Resorcinol Monoacetate 1,3-苯二醇單乙酸酯/290 (R)-Malic Acid (R)-蘋果酸/291 Rosmarinic Acid 迷迭香素/292 S-(5′-Adenosyl)-L-Homocysteine S-(5′-腺苷)-L-高半胱氨酸/293 S-(5′-Adenosyl)-L-Methionine S-腺苷基蛋氨酸/294 Salicylamide 水楊酰胺/295 Salicylic Acid 水楊酸/296 S-Carboxymethyl-L-Cysteine S-(羧甲基)-L-半胱氨酸/297 (S)-Dihydroorotic Acid L-氫化乳清酸/298 Serotonin 5-羥基色胺/299 Shikimic Acid 莽草酸/300 (S)-Malic Acid (S)-蘋果酸/301 Sn-Glycerol 3-Phosphate 甘油磷酸酯/302 Spermidine 亞精胺/303 Spermine 精胺/304 Sphinganine 鞘氨醇/305 (S,S)-Tartaric Acid (S,S)-酒石酸/306 Stachyose 水蘇糖/307 Stearic Acid 硬脂酸/308 Suberic Acid 辛二酸/309 Succinic Acid 琥珀酸/310 3-Sulfino-L-Alanine L-半胱亞磺酸/311 Taurine ;撬/312 Taurolithocholic Acid 牛磺石膽酸/313 Theobromine 可可堿/314 Theophylline 茶堿/315 Thiamine Monophosphate 硫胺素單磷酸/316 Thiamine Pyrophosphate Chloride 硫胺素焦磷酸鹽酸鹽/317 Thymidine 胸苷/318 Thymidine-5′-Diphospho-α-D-Glucose 胸苷-5′-二磷酸-α-D-葡萄糖/319 Thymidine-5′-Monophosphate 5′-磷酸胸苷/320 Thymine 胸腺嘧啶/321 Thyrotropin Releasing Hormone 促甲狀腺素釋放激素/322 Thyroxine 甲狀腺素/323 Trans-Cinnamic Acid 肉桂酸/324 Tricosanoic Acid 二十三烷酸/325 Trigonelline 葫蘆巴堿/326 3,3′,5′-Triiodothyronine 3,3′,5′-三碘甲狀腺原氨酸/327 Tryptamine 色胺/328 α-Tocopherol 維生素E/329 Tyramine 對羥基苯乙胺/330 Uracil 尿嘧啶/331 Uric Acid 尿酸/332 3-Ureidopropionic Acid 3-酰脲丙酸/333 Uridine 尿苷/334 Uridine 5′-Diphosphate 尿苷5′-二磷酸/335 Uridine 5′-Diphospho-galactose 尿苷5′-二磷酸半乳糖/336 Uridine 5′-Diphospho-glucuronic Acid 尿苷5′-二磷酸葡萄糖醛酸/337 Uridine 5′-Diphospho-N-Acetylgalactosamine 尿苷5′-二磷酸-N-乙酰氨基半乳糖/338 Uridine 5′-Diphospho-N-Acetylglucosamine 尿苷5′-二磷酸-N-乙酰半乳糖胺/339 Uridine-5′-Monophos-phate 尿苷5′-單磷酸/340 Urocanic Acid 尿刊酸/341 Vitamin D2 維生素D2/342 Xanthine 黃嘌呤/343 Xanthosine 黃嘌呤核苷/344 Xanthosine 5′-Mono-phosphate 黃嘌呤核苷 5′-單磷酸/345 Xanthurenic Acid 黃尿酸/346 索引/347
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